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Where does Poxet 60 mg start working in the body?
Where does Poxet 60 mg start working in the body?
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kirazmattson
960 posts
Apr 02, 2026
2:56 AM
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Poxet 60 mg, like Poxet 30 mg, contains dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI) specifically formulated for premature ejaculation. Here’s how and where it starts working in the body: Site of Action Central Nervous System (Brain & Spinal Cord) Dapoxetine acts primarily in the brain, especially in areas that control sexual reflexes, such as the medial preoptic area and the spinal cord. It increases serotonin levels at synapses, particularly at receptors that regulate ejaculation. By enhancing serotonin signaling, it delays the ejaculatory reflex, helping men last longer during sexual activity. Peripheral Effects Unlike ED drugs (e.g., sildenafil), POXET 60 MG does not act directly on the penis or blood vessels. Its effect is entirely neurological, so it requires sexual stimulation to work. How Quickly It Works After oral intake, dapoxetine is absorbed through the stomach and small intestine into the bloodstream. Peak levels are usually reached 1–3 hours after taking the pill. From there, it crosses the blood-brain barrier to start acting on serotonin pathways in the brain and spinal cord. Key point: Poxet 60 mg modulates the neural control of ejaculation, rather than physically altering blood flow or genital tissue.
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