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Why does Malegra 100 Mg  work for erectile  ?
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kirazmattson
813 posts
Jan 04, 2026
11:25 PM
Malegra 100 mg works for erectile dysfunction because it contains sildenafil citrate, a PDE5 inhibitor that helps improve blood flow to the penis. Here’s how it works in detail: Sexual stimulation triggers nitric oxide release in the penis. Nitric oxide activates an enzyme that produces cyclic GMP (cGMP), which relaxes the smooth muscles in the blood vessels of the penis. Relaxed blood vessels allow more blood to enter the penis, causing an erection. Sildenafil inhibits PDE5, an enzyme that normally breaks down cGMP. By blocking PDE5, sildenafil keeps cGMP active longer, so the erection can be maintained during sexual activity. Malegra 100 Mg is a high dose, usually recommended only if lower doses (like 25 mg or 50 mg) are insufficient and the patient can safely tolerate it. It’s taken about 30–60 minutes before sexual activity and works for around 4–6 hours. Important: It only works when there is sexual stimulation—taking it alone will not cause an erection. Men with certain heart conditions or those taking nitrates should not use it, as it can cause dangerously low blood pressure. If you want, I can also explain why the 100 mg dose is sometimes chosen over 50 mg in a simple, easy-to-understand way.


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