The term Microsoft Edge disable normally means that the user wants to stop the browser from starting up automatically, running in the background, or being opened by clicking on any link online. In order to disable automatic start-up of Edge, go to Windows Settings> Startup and disable Microsoft Edge. In order to minimize background processes, go to Settings > System > Startup boost and disable it. In case you want to use a different browser, choose the desired one under Settings > Apps > Default apps. Note that even after doing all these steps, Microsoft Edge will still remain on your PC as it is built into many Windows systems. Be careful not to delete the program files, as it may affect Windows functionality.